BDBM50058238 3-{[4-Oxo-5-(2-piperidin-4-yl-ethyl)-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazine-2-carbonyl]-amino}-propionic acid; hydrochloride::CHEMBL288521::CHEMBL540024

SMILES OC(=O)CCNC(=O)c1cc2C(=O)N(CCC3CCNCC3)CCn2n1

InChI Key InChIKey=RIMGWTGKJRYUQN-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058238   

TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50058238(CHEMBL540024 | CHEMBL288521 | 3-{[4-Oxo-5-(2-piper...)
Affinity DataKd:  590nMAssay Description:Displacement of L-736,622 from purified resting Fibrinogen ReceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50058238(CHEMBL540024 | CHEMBL288521 | 3-{[4-Oxo-5-(2-piper...)
Affinity DataIC50: 250nMAssay Description:Inhibition of fibrinogen binding to glycoprotein alpha IIb beta-3 integrin of activated plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article