BDBM50058517 2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-7H-1,3,7,10-tetraaza-phenanthren-9-one::CHEMBL57682

SMILES COc1cc(cc(OC)c1OC)-n1ccc2c(c1)c(=O)nc1nc(N)nc(N)c21

InChI Key InChIKey=PBZONEKKFAKAJA-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50058517   

TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058517(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-7H-1,3,7,1...)
Affinity DataIC50: 86nMAssay Description:Inhibitory concentration against Rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058517(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-7H-1,3,7,1...)
Affinity DataIC50: 240nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058517(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-7H-1,3,7,1...)
Affinity DataIC50: 240nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058517(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-7H-1,3,7,1...)
Affinity DataIC50: 520nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058517(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-7H-1,3,7,1...)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058517(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-7H-1,3,7,1...)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058517(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-7H-1,3,7,1...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory concentration against Pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058517(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-7H-1,3,7,1...)
Affinity DataIC50: 4.28E+3nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058517(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-7H-1,3,7,1...)
Affinity DataIC50: 4.28E+3nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed