BDBM50058519 2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-6,7-dihydro-5H-1,3,7,10-tetraaza-phenanthren-9-one::CHEMBL293512

SMILES COc1cc(cc(OC)c1OC)N1CCC2=c3c(N)nc(N)nc3=NC(=O)C2=C1

InChI Key InChIKey=FLHGSZGMDHCLCY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50058519   

TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058519(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-6,7-dihydr...)
Affinity DataIC50: 240nMAssay Description:Inhibitory concentration against Rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058519(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-6,7-dihydr...)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058519(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-6,7-dihydr...)
Affinity DataIC50: 4.28E+3nMAssay Description:Inhibitory concentration against Pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed