BDBM50058522 CHEMBL58597::Trifluoro-acetate2,4-diamino-7-(3,4,5-trimethoxy-phenyl)-7,8-dihydro-1,3,10-triaza-7-azonia-phenanthrene;

SMILES COc1cc(cc(OC)c1OC)[NH+]1Cc2cnc3nc(N)nc(N)c3c2C=C1

InChI Key InChIKey=BIGRVUZNHBDRLI-UHFFFAOYSA-O

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50058522   

TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058522(Trifluoro-acetate2,4-diamino-7-(3,4,5-trimethoxy-p...)
Affinity DataIC50: 470nMAssay Description:Inhibitory concentration against Rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058522(Trifluoro-acetate2,4-diamino-7-(3,4,5-trimethoxy-p...)
Affinity DataIC50: 760nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058522(Trifluoro-acetate2,4-diamino-7-(3,4,5-trimethoxy-p...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibitory concentration against Pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed