BDBM50059000 3-(3-Chloro-benzenesulfonyl)-1-phenyl-imidazolidine-2,4-dione::CHEMBL303871

SMILES Clc1cccc(c1)S(=O)(=O)N1C(=O)CN(C1=O)c1ccccc1

InChI Key InChIKey=DVKQEXDLGAQOLQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059000   

TargetChymase(Human)
Suntory

Curated by ChEMBL
LigandPNGBDBM50059000(3-(3-Chloro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin G(Human)
Suntory

Curated by ChEMBL
LigandPNGBDBM50059000(3-(3-Chloro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Suntory

Curated by ChEMBL
LigandPNGBDBM50059000(3-(3-Chloro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed