BDBM50059099 2-(4-Chloro-phenyl)-7-methyl-1H-[1,8]naphthyridin-4-one::CHEMBL48975

SMILES Cc1ccc2c(O)cc(nc2n1)-c1ccc(Cl)cc1

InChI Key InChIKey=RIVJLXUGNRBXCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059099   

TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059099(2-(4-Chloro-phenyl)-7-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin beta-2B chain(Bovine)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059099(2-(4-Chloro-phenyl)-7-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed