BDBM50059118 2-(4-Methoxy-phenyl)-6-methyl-1H-[1,8]naphthyridin-4-one::CHEMBL49424

SMILES COc1ccc(cc1)-c1cc(O)c2cc(C)cnc2n1

InChI Key InChIKey=WAQCUFMSLSYOIU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059118   

TargetTubulin beta-2B chain(Bovine)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059118(2-(4-Methoxy-phenyl)-6-methyl-1H-[1,8]naphthyridin...)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059118(2-(4-Methoxy-phenyl)-6-methyl-1H-[1,8]naphthyridin...)
Affinity DataIC50: 7.76E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed