BDBM50059581 CHEMBL406893::N,N-diCPM[D-Pro-10]Dyn A-(1-11)

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)N(CC1CC1)CC1CC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(O)=O

InChI Key InChIKey=XMFJUPAXGQSFIW-UHFFFAOYSA-N

Data  5 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50059581   

TargetKappa-type opioid receptor(Guinea pig)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059581(N,N-diCPM[D-Pro-10]Dyn A-(1-11) | CHEMBL406893)
Affinity DataIC50: 388nMAssay Description:Affinity against Opioid receptor kappa 2 was determined by measuring the inhibition of [3H]bremazocine binding to guinea pig cerebellar membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059581(N,N-diCPM[D-Pro-10]Dyn A-(1-11) | CHEMBL406893)
Affinity DataIC50: 29nMAssay Description:Binding affinity towards Opioid receptor kappa 1 using [3H]diprenorphine as radioligand in guinea pig cerebellar membrane in presence of 120 mM NaCl ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059581(N,N-diCPM[D-Pro-10]Dyn A-(1-11) | CHEMBL406893)
Affinity DataIC50: 3.30nMAssay Description:Binding affinity towards Opioid receptor kappa 1 using [3H]diprenorphine as radioligand in guinea pig cerebellar membrane in absence of 120 mM NaCl +...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059581(N,N-diCPM[D-Pro-10]Dyn A-(1-11) | CHEMBL406893)
Affinity DataKi:  0.190nMAssay Description:Affinity against Opioid receptor kappa 1 was determined by measuring the inhibition of [3H]bremazocine binding to guinea pig cerebellar membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059581(N,N-diCPM[D-Pro-10]Dyn A-(1-11) | CHEMBL406893)
Affinity DataKi:  2.60nMAssay Description:Affinity against Opioid receptor kappa 1 was determined by measuring the inhibition of [3H]U-69593 binding to guinea pig cerebellar membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059581(N,N-diCPM[D-Pro-10]Dyn A-(1-11) | CHEMBL406893)
Affinity DataKi:  3.90nMAssay Description:Affinity against Opioid receptor mu 1 was determined by measuring the inhibition of [3H]DAMGO binding to rat forebrain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059581(N,N-diCPM[D-Pro-10]Dyn A-(1-11) | CHEMBL406893)
Affinity DataKi:  44nMAssay Description:Affinity against Opioid receptor kappa 3 was determined by measuring the inhibition of [3H]NalBzoH binding to guinea pig cerebellar membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059581(N,N-diCPM[D-Pro-10]Dyn A-(1-11) | CHEMBL406893)
Affinity DataKi:  166nMAssay Description:Affinity against Opioid receptor delta 1 was determined by measuring the inhibition of [3H]DPDPE binding to rat forebrain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed