BDBM50059588 CHEMBL3393497

SMILES CCOC(=O)c1c2c(c[nH]1)[C@@H](C3=C(N2)CCCC3=O)c4cccc(c4)Oc5[nH]c6ccccc6n5

InChI Key InChIKey=YXMQIWJYPNBZJS-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059588   

TargetAurora kinase B(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059588(CHEMBL3393497)
Affinity DataIC50: 12nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059588(CHEMBL3393497)
Affinity DataIC50: 17nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora A (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)