BDBM50059748 2-Benzyl-1-butyl-9-phenyl-1,2-dihydro-pyrrolo[3,4-b]quinolin-3-one::CHEMBL429386

SMILES CCCCC1N(Cc2ccccc2)C(=O)c2nc3ccccc3c(c12)-c1ccccc1

InChI Key InChIKey=XHACLXKNCUGNGZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50059748   

TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50059748(2-Benzyl-1-butyl-9-phenyl-1,2-dihydro-pyrrolo[3,4-...)
Affinity DataIC50: 813nMAssay Description:In vitro binding affinity (pIC50) was tested against peripheral benzodiazepine receptor (PBR) in rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50059748(2-Benzyl-1-butyl-9-phenyl-1,2-dihydro-pyrrolo[3,4-...)
Affinity DataIC50: 810nMAssay Description:In vitro displacement of [3H]PK11195 from the peripheral benzodiazepine receptor (PBR) in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50059748(2-Benzyl-1-butyl-9-phenyl-1,2-dihydro-pyrrolo[3,4-...)
Affinity DataIC50: 810nMAssay Description:Test in vitro, for potential ability to displace [3H]1 from PBR in rat brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50059748(2-Benzyl-1-butyl-9-phenyl-1,2-dihydro-pyrrolo[3,4-...)
Affinity DataIC50: 810nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in rat brain cortex membrane incubated for 120 mins by liquid scintillation spectrometer methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed