BDBM50059751 8-Benzyl-5-phenyl-8,11-dihydro-6,8-diaza-cyclohepta[a]naphthalen-7-one::8-Benzyl-5-phenyl-8,9-dihydro-6,8-diaza-cyclohepta[a]naphthalen-7-one::CHEMBL15714

SMILES O=C1N(Cc2ccccc2)CC=Cc2c1nc(-c1ccccc1)c1ccccc21

InChI Key InChIKey=FJHVWULIKMATJO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50059751   

TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50059751(8-Benzyl-5-phenyl-8,11-dihydro-6,8-diaza-cyclohept...)
Affinity DataIC50: 45nMAssay Description:In vitro displacement of [3H]PK11195 from the peripheral benzodiazepine receptor (PBR) in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50059751(8-Benzyl-5-phenyl-8,11-dihydro-6,8-diaza-cyclohept...)
Affinity DataIC50: 45nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in rat brain cortex membrane incubated for 120 mins by liquid scintillation spectrometer methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50059751(8-Benzyl-5-phenyl-8,11-dihydro-6,8-diaza-cyclohept...)
Affinity DataIC50: 45nMAssay Description:Test in vitro, for potential ability to displace [3H]1 from PBR in rat brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50059751(8-Benzyl-5-phenyl-8,11-dihydro-6,8-diaza-cyclohept...)
Affinity DataIC50: 46nMAssay Description:In vitro binding affinity (pIC50) was tested against peripheral benzodiazepine receptor (PBR) in rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed