BDBM50059852 (S)-2-((S)-2-((S)-2-((R)-2-amino-3-mercaptopropylamino)-3-methylbutylamino)-3-phenylpropanamido)-4-(methylthio)butanoic acid::(S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methyl-butylamino]-3-phenyl-propionylamino}-4-methylsulfanyl-butyric acid::CHEMBL91722::N-[2(S)-[2(R)-amino-3-mercaptopropylamino]-3-methylbutyl]-Phe-Met-OH

SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC[C@@H](NC[C@@H](N)CS)C(C)C)C(O)=O

InChI Key InChIKey=QISLMXIYRQCLIR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50059852   

TargetSqualene synthase(Bovine)
Cold Spring Harbor Laboratory

Curated by ChEMBL
LigandPNGBDBM50059852(N-[2(S)-[2(R)-amino-3-mercaptopropylamino]-3-methy...)
Affinity DataIC50: 21nMAssay Description:Compound was evaluated for concentration that caused 50% inhibition of bovine FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Cold Spring Harbor Laboratory

Curated by ChEMBL
LigandPNGBDBM50059852(N-[2(S)-[2(R)-amino-3-mercaptopropylamino]-3-methy...)
Affinity DataIC50: 300nMAssay Description:Compound was evaluated for concentration that caused 50% inhibition of yeast Farnesyltransferase (expressed as a GST fusion protein in Escherichia co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50059852(N-[2(S)-[2(R)-amino-3-mercaptopropylamino]-3-methy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Ras processing in v-Ras-transformed cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50059852(N-[2(S)-[2(R)-amino-3-mercaptopropylamino]-3-methy...)
Affinity DataIC50: 21nMAssay Description:Inhibition of bovine FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50059852(N-[2(S)-[2(R)-amino-3-mercaptopropylamino]-3-methy...)
Affinity DataIC50: 21nMAssay Description:In vitro inhibition of bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article