BDBM50059917 CHEMBL3394361

SMILES COCCc1ccc(cn1)-c1c(nc2c(nccn12)N1CCOCC1)C(C)C

InChI Key InChIKey=DWDNIIGWJSBLHJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50059917   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Janssen Pharmaceutica

Curated by ChEMBL

LigandBDBM50059917(CHEMBL3394361)Copy SMILESCopy InChI

Affinity DataIC50: 339nMAssay Description:Inhibition of rat recombinant PDE10A expressed in Sf9 cells using [3H]cAMP substrate incubated for 60 mins by topcount scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/3/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL