BDBM50059926 8-(2,6-Dichloro-phenyl)-9H-purine-2,6-diamine::CHEMBL318601

SMILES Nc1nc(N)c2[nH]c(nc2n1)-c1c(Cl)cccc1Cl

InChI Key InChIKey=ZBIYAIOEBKNMQY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059926   

TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059926(8-(2,6-Dichloro-phenyl)-9H-purine-2,6-diamine | CH...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059926(8-(2,6-Dichloro-phenyl)-9H-purine-2,6-diamine | CH...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059926(8-(2,6-Dichloro-phenyl)-9H-purine-2,6-diamine | CH...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed