BDBM50059928 8-Pyridin-4-yl-9H-purine-2,6-diamine::CHEMBL317618

SMILES Nc1nc(N)c2[nH]c(nc2n1)-c1ccncc1

InChI Key InChIKey=FRFATUHEQSVWHE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059928   

TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059928(8-Pyridin-4-yl-9H-purine-2,6-diamine | CHEMBL31761...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059928(8-Pyridin-4-yl-9H-purine-2,6-diamine | CHEMBL31761...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059928(8-Pyridin-4-yl-9H-purine-2,6-diamine | CHEMBL31761...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed