BDBM50059930 8-(4-Methoxy-naphthalen-1-yl)-9H-purine-2,6-diamine::CHEMBL106383

SMILES COc1ccc(-c2nc3nc(N)nc(N)c3[nH]2)c2ccccc12

InChI Key InChIKey=ROWVTKSVAKQZPC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059930   

TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059930(8-(4-Methoxy-naphthalen-1-yl)-9H-purine-2,6-diamin...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059930(8-(4-Methoxy-naphthalen-1-yl)-9H-purine-2,6-diamin...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059930(8-(4-Methoxy-naphthalen-1-yl)-9H-purine-2,6-diamin...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed