BDBM50059931 8-(2,4,6-Trimethoxy-phenyl)-9H-purine-2,6-diamine::8-(2,4,6-trimethoxyphenyl)-9H-purine-2,6-diamine::CHEMBL103474

SMILES COc1cc(OC)c(-c2nc3nc(N)nc(N)c3[nH]2)c(OC)c1

InChI Key InChIKey=DGDMBWNOPVGWKG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50059931   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059931(8-(2,4,6-trimethoxyphenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 840nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059931(8-(2,4,6-trimethoxyphenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 840nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059931(8-(2,4,6-trimethoxyphenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059931(8-(2,4,6-trimethoxyphenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059931(8-(2,4,6-trimethoxyphenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 3.15E+4nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed