BDBM50059933 8-(3,4,5-Trimethoxy-phenyl)-9H-purine-2,6-diamine::8-(3,4,5-trimethoxyphenyl)-9H-purine-2,6-diamine::CHEMBL431257

SMILES COc1cc(cc(OC)c1OC)-c1nc2nc(N)nc(N)c2[nH]1

InChI Key InChIKey=QPWGTISXOSFSHJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50059933   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059933(8-(3,4,5-Trimethoxy-phenyl)-9H-purine-2,6-diamine ...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059933(8-(3,4,5-Trimethoxy-phenyl)-9H-purine-2,6-diamine ...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059933(8-(3,4,5-Trimethoxy-phenyl)-9H-purine-2,6-diamine ...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059933(8-(3,4,5-Trimethoxy-phenyl)-9H-purine-2,6-diamine ...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059933(8-(3,4,5-Trimethoxy-phenyl)-9H-purine-2,6-diamine ...)
Affinity DataIC50: 5.94E+4nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed