BDBM50059934 8-((2,5-dimethoxyphenylamino)methyl)-9H-purine-2,6-diamine::8-[(2,5-Dimethoxy-phenylamino)-methyl]-9H-purine-2,6-diamine::CHEMBL102432

SMILES COc1ccc(OC)c(NCc2nc3nc(N)nc(N)c3[nH]2)c1

InChI Key InChIKey=LCKXCYYLUZCCMT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50059934   

TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059934(8-((2,5-dimethoxyphenylamino)methyl)-9H-purine-2,6...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059934(8-((2,5-dimethoxyphenylamino)methyl)-9H-purine-2,6...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059934(8-((2,5-dimethoxyphenylamino)methyl)-9H-purine-2,6...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059934(8-((2,5-dimethoxyphenylamino)methyl)-9H-purine-2,6...)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059934(8-((2,5-dimethoxyphenylamino)methyl)-9H-purine-2,6...)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed