BDBM50059937 8-(4,5-Dimethoxy-2-nitro-phenyl)-9H-purine-2,6-diamine::CHEMBL101378

SMILES COc1cc(-c2nc3nc(N)nc(N)c3[nH]2)c(cc1OC)[N+]([O-])=O

InChI Key InChIKey=RODHWFQOANIJGV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059937   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059937(8-(4,5-Dimethoxy-2-nitro-phenyl)-9H-purine-2,6-dia...)
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059937(8-(4,5-Dimethoxy-2-nitro-phenyl)-9H-purine-2,6-dia...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059937(8-(4,5-Dimethoxy-2-nitro-phenyl)-9H-purine-2,6-dia...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed