BDBM50059939 8-(2,5-Dimethoxy-phenyl)-9H-purine-2,6-diamine::8-(2,5-dimethoxyphenyl)-9H-purine-2,6-diamine::CHEMBL106070

SMILES COc1ccc(OC)c(c1)-c1nc2nc(N)nc(N)c2[nH]1

InChI Key InChIKey=FFAMOOJMNMXIFW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50059939   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059939(8-(2,5-Dimethoxy-phenyl)-9H-purine-2,6-diamine | 8...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059939(8-(2,5-Dimethoxy-phenyl)-9H-purine-2,6-diamine | 8...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059939(8-(2,5-Dimethoxy-phenyl)-9H-purine-2,6-diamine | 8...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059939(8-(2,5-Dimethoxy-phenyl)-9H-purine-2,6-diamine | 8...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059939(8-(2,5-Dimethoxy-phenyl)-9H-purine-2,6-diamine | 8...)
Affinity DataIC50: 3.74E+4nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed