BDBM50059982 (1E,6E)-1,7-Bis-(4-methoxy-phenyl)-hepta-1,6-diene-3,5-dione::CHEMBL103006

SMILES COc1ccc(C=CC(=O)CC(=O)C=Cc2ccc(OC)cc2)cc1

InChI Key InChIKey=JFOLIEXFFOBCSM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50059982   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50059982((1E,6E)-1,7-Bis-(4-methoxy-phenyl)-hepta-1,6-diene...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of 3'- processing activity of HIV-1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50059982((1E,6E)-1,7-Bis-(4-methoxy-phenyl)-hepta-1,6-diene...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition incubated for 15 mins by FRET as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50059982((1E,6E)-1,7-Bis-(4-methoxy-phenyl)-hepta-1,6-diene...)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of human recombinant GSK3-beta using prephosphorylated polypeptide as substrate incubated for 30 mins by Glo-type luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50059982((1E,6E)-1,7-Bis-(4-methoxy-phenyl)-hepta-1,6-diene...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of strand transfer activity of HIV-1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed