BDBM50060471 4-Chloro-5,6-dihydro-benzo[c]acridin-7-ylamine::CHEMBL333011

SMILES Nc1c2CCc3c(Cl)cccc3-c2nc2ccccc12

InChI Key InChIKey=WTSAZZJEZMYESQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50060471   

TargetCholinesterase(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060471(4-Chloro-5,6-dihydro-benzo[c]acridin-7-ylamine | C...)
Affinity DataIC50: 1.03E+4nMAssay Description:In vitro inhibition of Butyrylcholinesterase from human plasma.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060471(4-Chloro-5,6-dihydro-benzo[c]acridin-7-ylamine | C...)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of neuronal uptake of 5 - Hydroxytryptamine in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060471(4-Chloro-5,6-dihydro-benzo[c]acridin-7-ylamine | C...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of neuronal uptake of Noradrenaline in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060471(4-Chloro-5,6-dihydro-benzo[c]acridin-7-ylamine | C...)
Affinity DataIC50: 1.44E+5nMAssay Description:In vitro inhibition of acetylcholinesterase, isolated from rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed