BDBM50060478 3-Methoxy-5,6-dihydro-benzo[c]acridin-7-ylamine::3-methoxy-5,6-dihydrobenzo[c]acridin-7-amine::CHEMBL118033

SMILES COc1ccc-2c(CCc3c(N)c4ccccc4nc-23)c1

InChI Key InChIKey=OEZAABQDNYILBC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50060478   

TargetTransporter(Rat)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060478(3-Methoxy-5,6-dihydro-benzo[c]acridin-7-ylamine | ...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of neuronal uptake of Noradrenaline in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060478(3-Methoxy-5,6-dihydro-benzo[c]acridin-7-ylamine | ...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of neuronal uptake of 5 - Hydroxytryptamine in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50060478(3-Methoxy-5,6-dihydro-benzo[c]acridin-7-ylamine | ...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060478(3-Methoxy-5,6-dihydro-benzo[c]acridin-7-ylamine | ...)
Affinity DataIC50: 4.75E+4nMAssay Description:In vitro inhibition of acetylcholinesterase, isolated from rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed