BDBM50060714 6-Bromo-5-{[(2,5-dimethoxy-phenyl)-methyl-amino]-methyl}-thieno[2,3-d]pyrimidine-2,4-diamine::CHEMBL433021

SMILES COc1ccc(OC)c(c1)N(C)Cc1c(Br)sc2nc(N)nc(N)c12

InChI Key InChIKey=MWGRAFGHTLYYMR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50060714   

TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060714(6-Bromo-5-{[(2,5-dimethoxy-phenyl)-methyl-amino]-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Pneumocystis carinii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060714(6-Bromo-5-{[(2,5-dimethoxy-phenyl)-methyl-amino]-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Toxoplasma gondii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060714(6-Bromo-5-{[(2,5-dimethoxy-phenyl)-methyl-amino]-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat liver Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed