BDBM50060840 CHEMBL340299::N-[(R)-5-(6-Cyclopentylamino-purin-9-yl)-4-hydroxy-2-hydroxymethyl-tetrahydro-furan-3-yl]-4-methoxy-benzamide

SMILES COc1ccc(cc1)C(=O)N[C@H]1C(CO)OC(C1O)n1cnc2c(NC3CCCC3)ncnc12

InChI Key InChIKey=QEWGNGQUYQBUKO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50060840   

TargetAdenosine receptor A1(Rat)
University of Ghent

Curated by ChEMBL
LigandPNGBDBM50060840(N-[(R)-5-(6-Cyclopentylamino-purin-9-yl)-4-hydroxy...)
Affinity DataKi:  130nMAssay Description:Affinity for adenosine A1 receptor was determined, in the presence of GTP in rat brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Ghent

Curated by ChEMBL
LigandPNGBDBM50060840(N-[(R)-5-(6-Cyclopentylamino-purin-9-yl)-4-hydroxy...)
Affinity DataKi:  200nMAssay Description:Affinity for adenosine A1 receptor was determined, in the absence of GTP in rat cortical membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
University of Ghent

Curated by ChEMBL
LigandPNGBDBM50060840(N-[(R)-5-(6-Cyclopentylamino-purin-9-yl)-4-hydroxy...)
Affinity DataKi:  770nMAssay Description:Affinity for adenosine A2a receptor was determined on rat striatal membrane using [3H]-CGS- 21680 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed