BDBM50061165 CHEMBL3393719

SMILES CS(=O)(=O)c1ccc(c(F)c1)-c1ccc2[nH]nc(-c3cncc(O[C@H]4CNCCC44CC4)n3)c2c1

InChI Key InChIKey=CUEWSGPOORVNOX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061165   

TargetSerine/threonine-protein kinase pim-1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061165(CHEMBL3393719)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of full length recombinant Pim-1 (unknown origin) assessed as phosphorylation of biotinylated-BAD peptide at Serine 112 residueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061165(CHEMBL3393719)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of full length recombinant Pim-2 (unknown origin) assessed as phosphorylation of biotinylated-BAD peptide at Serine 112 residueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
LigandPNGBDBM50061165(CHEMBL3393719)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed