BDBM50061177 CHEMBL3393705

SMILES CC1(C)CCNCC1Oc1cncc(n1)-c1n[nH]c2ccc(cc12)-c1c(F)cccc1F

InChI Key InChIKey=KUFLSJFOFGKCHC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061177   

TargetSerine/threonine-protein kinase pim-1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061177(CHEMBL3393705)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length recombinant Pim-1 (unknown origin) assessed as phosphorylation of biotinylated-BAD peptide at Serine 112 residueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061177(CHEMBL3393705)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length recombinant Pim-3 (unknown origin) assessed as phosphorylation of biotinylated-BAD peptide at Serine 112 residueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061177(CHEMBL3393705)
Affinity DataIC50: 16nMAssay Description:Inhibition of full length recombinant Pim-2 (unknown origin) assessed as phosphorylation of biotinylated-BAD peptide at Serine 112 residueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed