BDBM50061223 CHEMBL3393715

SMILES C1CC11CCNC[C@@H]1Oc1cncc(n1)-c1n[nH]c2ccc(cc12)-c1nccs1

InChI Key InChIKey=GUTPGVLUDRSUIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061223   

TargetSerine/threonine-protein kinase pim-1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061223(CHEMBL3393715)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length recombinant Pim-1 (unknown origin) assessed as phosphorylation of biotinylated-BAD peptide at Serine 112 residueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061223(CHEMBL3393715)
Affinity DataIC50: 8nMAssay Description:Inhibition of full length recombinant Pim-2 (unknown origin) assessed as phosphorylation of biotinylated-BAD peptide at Serine 112 residueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed