BDBM50061259 1-(4-fluorophenyl)-4-[1-methylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-butanone::CHEMBL405524

SMILES CN1CC2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)c2ccccc12

InChI Key InChIKey=APDLVICBNVGZDB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061259   

TargetSigma non-opioid intracellular receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50061259(1-(4-fluorophenyl)-4-[1-methylspiro[2,3-dihydro-1H...)
Affinity DataKi:  110nMAssay Description:Sigma-1 binding assay was done in guinea pig membranes by labeling the binding site with [3H](+)-pentazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50061259(1-(4-fluorophenyl)-4-[1-methylspiro[2,3-dihydro-1H...)
Affinity DataKi:  570nMAssay Description:Binding to vesicular acetylcholine transporter of torpedo synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed