BDBM50061268 (2R,4R)-1-[(R)-2-(2-Aza-tricyclo[3.3.1.1*3,7*]dec-2-yloxycarbonylamino)-3-(1H-indol-3-yl)-2-methyl-propionyl]-4-(4-iodo-phenoxy)-pyrrolidine-2-carboxylic acid::CHEMBL337933

SMILES C[C@](Cc1c[nH]c2ccccc12)(NC(=O)ON1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(=O)N1C[C@@H](C[C@@H]1C(O)=O)Oc1ccc(I)cc1

InChI Key

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061268   

TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50061268((2R,4R)-1-[(R)-2-(2-Aza-tricyclo[3.3.1.1*3,7*]dec-...)
Affinity DataKi:  45nMAssay Description:Compound was tested for the affinity against Cholecystokinin type B receptor on guinea pig cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Rat)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50061268((2R,4R)-1-[(R)-2-(2-Aza-tricyclo[3.3.1.1*3,7*]dec-...)
Affinity DataIC50: 56nMAssay Description:Inhibition of inositol phosphate production induced by Cholecystokinin type B receptor (0.5 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Rat)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50061268((2R,4R)-1-[(R)-2-(2-Aza-tricyclo[3.3.1.1*3,7*]dec-...)
Affinity DataKi:  75nMAssay Description:Compound was tested for binding affinity against rat brain Cholecystokinin type B receptor expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed