BDBM50061426 1-[4,6-Dichloro-3-(4-chloro-benzyloxy)-2,3-dihydro-benzo[b]thiophen-2-ylmethyl]-1H-imidazole::CHEMBL133288

SMILES Clc1ccc(COC2C(Cn3ccnc3)Sc3cc(Cl)cc(Cl)c23)cc1

InChI Key InChIKey=HLISQAYPWNMIHC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061426   

LigandPNGBDBM50061426(1-[4,6-Dichloro-3-(4-chloro-benzyloxy)-2,3-dihydro...)
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibitory activity against Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061426(1-[4,6-Dichloro-3-(4-chloro-benzyloxy)-2,3-dihydro...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against recombinant human farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed