BDBM50061437 1-[(2R,3R)-5,7-Dichloro-3-(2-chloro-thiophen-3-ylmethoxy)-2,3-dihydro-benzo[b]thiophen-2-ylmethyl]-1H-imidazole::CHEMBL335758

SMILES Clc1sccc1CO[C@H]1[C@@H](Cn2ccnc2)Sc2c1cc(Cl)cc2Cl

InChI Key InChIKey=JHKCVYJSSNDGMS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061437   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061437(1-[(2R,3R)-5,7-Dichloro-3-(2-chloro-thiophen-3-ylm...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against recombinant human farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50061437(1-[(2R,3R)-5,7-Dichloro-3-(2-chloro-thiophen-3-ylm...)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibitory activity against Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed