BDBM50061439 1-[(2R,3R)-3-(2-Chloro-thiophen-3-ylmethoxy)-5-fluoro-2,3-dihydro-benzo[b]thiophen-2-ylmethyl]-1H-imidazole::CHEMBL129853

SMILES Fc1ccc2S[C@H](Cn3ccnc3)[C@H](OCc3ccsc3Cl)c2c1

InChI Key InChIKey=WZBHBMIOGBUMBW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061439   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061439(1-[(2R,3R)-3-(2-Chloro-thiophen-3-ylmethoxy)-5-flu...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity against recombinant human farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50061439(1-[(2R,3R)-3-(2-Chloro-thiophen-3-ylmethoxy)-5-flu...)
Affinity DataIC50: 3.41E+4nMAssay Description:Inhibitory activity against Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed