BDBM50061446 1-[(1R,2R)-1-(2-Chloro-thiophen-3-ylmethoxy)-1,2,6,7,8,9-hexahydro-naphtho[2,1-b]thiophen-2-ylmethyl]-1H-imidazole::CHEMBL132564

SMILES Clc1sccc1CO[C@H]1[C@@H](Cn2ccnc2)Sc2ccc3CCCCc3c12

InChI Key InChIKey=YDIMTSKBEXCNQL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061446   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061446(1-[(1R,2R)-1-(2-Chloro-thiophen-3-ylmethoxy)-1,2,6...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against recombinant human farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50061446(1-[(1R,2R)-1-(2-Chloro-thiophen-3-ylmethoxy)-1,2,6...)
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibitory activity against Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed