BDBM50061449 1-[5-Chloro-3-(2,4-dichloro-benzyloxy)-2,3-dihydro-benzo[b]thiophen-2-ylmethyl]-1H-imidazole::CHEMBL131542

SMILES Clc1ccc2SC(Cn3ccnc3)C(OCc3ccc(Cl)cc3Cl)c2c1

InChI Key InChIKey=QUQDOQTVANCRAB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061449   

LigandPNGBDBM50061449(1-[5-Chloro-3-(2,4-dichloro-benzyloxy)-2,3-dihydro...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061449(1-[5-Chloro-3-(2,4-dichloro-benzyloxy)-2,3-dihydro...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against recombinant human farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed