BDBM50061461 8-Chloro-7-((2R,3R)-6-chloro-2-imidazol-1-ylmethyl-2,3-dihydro-benzo[b]thiophen-3-yloxymethyl)-[1,3]dioxolo[4,5-g]quinoline::CHEMBL132572

SMILES Clc1ccc2[C@@H](OCc3cnc4cc5OCOc5cc4c3Cl)[C@@H](Cn3ccnc3)Sc2c1

InChI Key InChIKey=INWRHSFSXDNDLS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061461   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061461(8-Chloro-7-((2R,3R)-6-chloro-2-imidazol-1-ylmethyl...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of Farnesyltransferase (FPT) in FPT Ras/TCA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50061461(8-Chloro-7-((2R,3R)-6-chloro-2-imidazol-1-ylmethyl...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061461(8-Chloro-7-((2R,3R)-6-chloro-2-imidazol-1-ylmethyl...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity against recombinant human farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed