BDBM50061464 1-(((2R,3R)-3-(2,4-dichlorobenzyloxy)-5-fluoro-2,3-dihydrobenzo[b]thiophen-2-yl)methyl)-1H-imidazole::1-[(2R,3R)-3-(2,4-Dichloro-benzyloxy)-5-fluoro-2,3-dihydro-benzo[b]thiophen-2-ylmethyl]-1H-imidazole::CHEMBL130433

SMILES Fc1ccc2S[C@H](Cn3ccnc3)[C@H](OCc3ccc(Cl)cc3Cl)c2c1

InChI Key InChIKey=ISAKNYLLDUELLC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061464   

LigandPNGBDBM50061464(1-(((2R,3R)-3-(2,4-dichlorobenzyloxy)-5-fluoro-2,3...)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibitory activity against Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061464(1-(((2R,3R)-3-(2,4-dichlorobenzyloxy)-5-fluoro-2,3...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against recombinant human farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed