BDBM50061474 1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-pyridin-4-yl-ethanone::CHEMBL133121

SMILES Clc1ccc2C(C3CCN(CC3)C(=O)Cc3ccncc3)c3ncccc3CCc2c1

InChI Key InChIKey=JDVAFNYVHBODGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50061474   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061474(1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohept...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against recombinant human farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed