BDBM50061485 2-Chloro-3-((2R,3R)-6-chloro-2-imidazol-1-ylmethyl-2,3-dihydro-benzo[b]thiophen-3-yloxymethyl)-pyridine::CHEMBL445906

SMILES Clc1ccc2[C@@H](OCc3cccnc3Cl)[C@@H](Cn3ccnc3)Sc2c1

InChI Key InChIKey=NLQMHNNHORVRTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061485   

LigandPNGBDBM50061485(2-Chloro-3-((2R,3R)-6-chloro-2-imidazol-1-ylmethyl...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibitory activity against Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061485(2-Chloro-3-((2R,3R)-6-chloro-2-imidazol-1-ylmethyl...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against recombinant human farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed