BDBM50062157 6,7,8,9-Tetrahydro-2-thia-1,3,8-triaza-cyclopenta[a]naphthalene::CHEMBL15936

SMILES C1Cc2ccc3nsnc3c2CN1

InChI Key InChIKey=RMTXTNQLNMQOTD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50062157   

TargetMuscarinic acetylcholine receptor M2(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50062157(6,7,8,9-Tetrahydro-2-thia-1,3,8-triaza-cyclopenta[...)
Affinity DataIC50: 6.70E+3nMAssay Description:Compound was evaluated for its ability to displace [3H]- N-methyl-scopolamine ([3H]NMS) binding to cloned CHO cell lines expressing Muscarinic acetyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50062157(6,7,8,9-Tetrahydro-2-thia-1,3,8-triaza-cyclopenta[...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was evaluated for its ability to displace [3H]- N-methyl-scopolamine ([3H]NMS) binding to cloned CHO cell lines expressing Muscarinic acetyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50062157(6,7,8,9-Tetrahydro-2-thia-1,3,8-triaza-cyclopenta[...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was evaluated for its ability to displace [3H]N-methylscopolamine ([3H]NMS) binding to cloned CHO cell lines expressing Muscarinic acetylcho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50062157(6,7,8,9-Tetrahydro-2-thia-1,3,8-triaza-cyclopenta[...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was evaluated for its ability to displace [3H]N-methylscopolamine ([3H]NMS) binding to cloned CHO cell lines expressing Muscarinic acetylcho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50062157(6,7,8,9-Tetrahydro-2-thia-1,3,8-triaza-cyclopenta[...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was evaluated for its ability to displace [3H]- N-methyl-scopolamine ([3H]-NMS) binding to cloned CHO cell lines expressing Muscarinic acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed