BDBM50062307 (R)-N*4*-Hydroxy-2-isobutyl-N*1*-((R)-1-methylcarbamoyl-2-naphthalen-2-yl-ethyl)-succinamide::CHEMBL71618

SMILES CNC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](CC(C)C)CC(=O)NO

InChI Key InChIKey=USFNQSYWKLKGHX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062307   

Target72 kDa type IV collagenase(Human)
Glycomed

Curated by ChEMBL
LigandPNGBDBM50062307((R)-N*4*-Hydroxy-2-isobutyl-N*1*-((R)-1-methylcarb...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity towards 72 kDa gelatinase (Matrix metalloprotease-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glycomed

Curated by ChEMBL
LigandPNGBDBM50062307((R)-N*4*-Hydroxy-2-isobutyl-N*1*-((R)-1-methylcarb...)
Affinity DataKi:  0.990nMAssay Description:The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloprotease-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Glycomed

Curated by ChEMBL
LigandPNGBDBM50062307((R)-N*4*-Hydroxy-2-isobutyl-N*1*-((R)-1-methylcarb...)
Affinity DataKi:  1.30nMAssay Description:The compound was tested for its binding affinity towards neutrophil collagenase (Matrix metalloprotease-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed