BDBM50062372 (2S,3R,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4-fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane::(2S,3R,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4-fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane::CHEMBL88301

SMILES Fc1ccc(cc1)[C@@H]1CC2CCC(N2)[C@H]1COc1ccc2OCOc2c1

InChI Key

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50062372   

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062372((2S,3R,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 3.86nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062372((2S,3R,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 3.90nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062372((2S,3R,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062372((2S,3R,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 5.62nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062372((2S,3R,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062372((2S,3R,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 14.4nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed