BDBM50062418 5-(6-Bromo-pyridin-3-yl)-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL102179

SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(Br)nc4)c3c12

InChI Key InChIKey=IZMLMXPILRMTIR-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062418   

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062418(5-(6-Bromo-pyridin-3-yl)-2,2,4-trimethyl-2,5-dihyd...)
Affinity DataKi:  3.90nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062418(5-(6-Bromo-pyridin-3-yl)-2,2,4-trimethyl-2,5-dihyd...)
Affinity DataIC50: 54nMAssay Description:Antagonistic activity was determined in Human progesterone receptor(hPR) of CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062418(5-(6-Bromo-pyridin-3-yl)-2,2,4-trimethyl-2,5-dihyd...)
Affinity DataEC50:  3.90E+3nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed