BDBM50062802 CHEMBL149424::{(S)-1-[2-(4-Aminomethyl-benzoylamino)-acetyl]-4-carboxymethyl-3-oxo-piperazin-2-yl}-acetic acid

SMILES NCc1ccc(cc1)C(=O)NCC(=O)N1CCN(CC(O)=O)C(=O)[C@@H]1CC(O)=O

InChI Key InChIKey=CBELHQKPOFWOOH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062802   

TargetIntegrin alpha-IIb/beta-3(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062802({(S)-1-[2-(4-Aminomethyl-benzoylamino)-acetyl]-4-c...)
Affinity DataIC50: 18nMAssay Description:Ability to inhibit binding of biotin-labeled human fibrinogen to immobilized fibrinogen receptor purified from human erythroleukemia (HEL) cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062802({(S)-1-[2-(4-Aminomethyl-benzoylamino)-acetyl]-4-c...)
Affinity DataIC50: 2.80E+3nMAssay Description:Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of human platelets by 50% in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062802({(S)-1-[2-(4-Aminomethyl-benzoylamino)-acetyl]-4-c...)
Affinity DataIC50: 2.90E+3nMAssay Description:Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of guinea pig platelets by 50% in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed