BDBM50062812 CHEMBL356739::{(S)-4-Carboxymethyl-1-[2-(5-guanidino-pentanoylamino)-acetyl]-3-oxo-piperazin-2-yl}-acetic acid

SMILES NC(=N)NCCCCC(=O)NCC(=O)N1CCN(CC(O)=O)C(=O)[C@@H]1CC(O)=O

InChI Key InChIKey=ULYCDWSKBGWSID-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062812   

TargetIntegrin alpha-IIb/beta-3(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062812({(S)-4-Carboxymethyl-1-[2-(5-guanidino-pentanoylam...)
Affinity DataIC50: 46nMAssay Description:Ability to inhibit binding of biotin-labeled human fibrinogen to immobilized fibrinogen receptor purified from human erythroleukemia (HEL) cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062812({(S)-4-Carboxymethyl-1-[2-(5-guanidino-pentanoylam...)
Affinity DataIC50: 3.60E+3nMAssay Description:Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of human platelets by 50% in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062812({(S)-4-Carboxymethyl-1-[2-(5-guanidino-pentanoylam...)
Affinity DataIC50: 5.30E+3nMAssay Description:Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of guinea pig platelets by 50% in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed