BDBM50063403 4-{2-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-piperidine-1-carboxylic acid phenyl ester::CHEMBL354131

SMILES Clc1ccc2C(N3CCN(CC3)C(=O)CC3CCN(CC3)C(=O)Oc3ccccc3)c3ncc(Br)cc3CCc2c1

InChI Key InChIKey=PHLAKICDEGLMTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50063403   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063403(4-{2-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,...)
Affinity DataIC50: 340nMAssay Description:In vitro inhibition of farnesyltransferase farnesylation of the H-ras oncogeneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed