BDBM50063508 CHEMBL3398500

SMILES Cc1ccsc1C(=CCCN1CCC[C@@H]1[C@@H](O)C(=O)O)c1sccc1C

InChI Key InChIKey=UGFPHZFFKAAVIJ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50063508   

TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063508BDBM50063508(CHEMBL3398500)
Affinity DataKi:  1.07E+3nMAssay Description:Binding affinity to mouse GAT1 expressed in HEK293 cells using NO71156 as unlabelled marker by LC-ESI-MS-MS based competitive MS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063508BDBM50063508(CHEMBL3398500)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity to human GAT1 expressed in HEK293 cells using NO71156 as unlabelled marker by LC-ESI-MS-MS based competitive MS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063508BDBM50063508(CHEMBL3398500)
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells by [3H]GABA uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50063508BDBM50063508(CHEMBL3398500)
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of human GAT1 expressed in HEK293 cells by [3H]GABA uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed