BDBM50063624 1-(4-Bromo-phenyl)-3-{2-[3-(3-isopropoxy-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-yl]-ethyl}-urea::CHEMBL266598

SMILES CC(C)Oc1cccc(c1)-n1c(CCNC(=O)Nc2ccc(Br)cc2)nc2ccccc2c1=O

InChI Key InChIKey=JMVWXYXYSBRGFH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50063624   

TargetGastrin/cholecystokinin type B receptor(Mouse)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50063624(1-(4-Bromo-phenyl)-3-{2-[3-(3-isopropoxy-phenyl)-4...)
Affinity DataIC50: 585nMAssay Description:Binding affinity towards Cholecystokinin type B receptor (CCK-B) receptor in mouse cerebral cortex using [125I]bolton Hunter CCK-8 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50063624(1-(4-Bromo-phenyl)-3-{2-[3-(3-isopropoxy-phenyl)-4...)
Affinity DataIC50: 1.63E+3nMAssay Description:Binding affinity towards Cholecystokinin type A receptor (CCK-A) receptor from rat pancreas using [125I]bolton Hunter CCK-8 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50063624(1-(4-Bromo-phenyl)-3-{2-[3-(3-isopropoxy-phenyl)-4...)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of specific binding of [125 I] Bolton Hunter CCK-8 to Cholecystokinin type A receptor in the rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetGastrin/cholecystokinin type B receptor(Mouse)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50063624(1-(4-Bromo-phenyl)-3-{2-[3-(3-isopropoxy-phenyl)-4...)
Affinity DataIC50: 585nMAssay Description:Inhibition of [125 I]CCK-8 binding to Cholecystokinin type B receptor of mouse cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article