BDBM50063992 5-((methyl(3,4,5-trichlorophenyl)amino)methyl)furo[2,3-d]pyrimidine-2,4-diamine::5-{[Methyl-(3,4,5-trichloro-phenyl)-amino]-methyl}-furo[2,3-d]pyrimidine-2,4-diamine::CHEMBL278110

SMILES CN(Cc1coc2nc(N)nc(N)c12)c1cc(Cl)c(Cl)c(Cl)c1

InChI Key InChIKey=DVXJBULZBVBIFK-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50063992   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063992(5-{[Methyl-(3,4,5-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase from Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063992(5-{[Methyl-(3,4,5-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063992(5-{[Methyl-(3,4,5-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063992(5-{[Methyl-(3,4,5-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 3.43E+4nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063992(5-{[Methyl-(3,4,5-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 3.43E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063992(5-{[Methyl-(3,4,5-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 3.43E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063992(5-{[Methyl-(3,4,5-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 2.84E+5nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063992(5-{[Methyl-(3,4,5-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 2.84E+5nMAssay Description:Inhibitory activity against dihydrofolate reductase from pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed